Genetics & Genetic Models of Hypertension
Moderator: Curt D. Sigmund, PhD, FAHA, Milwaukee, Wisconsin
10:00 am
Activation of Neuronal At1R Exacerbates Hypertension-Induced Reduction in Neuronal Function
Jiaxi Xu, Xi'an Jiaotong Univ, Xi'an, China; Eric D. Lazartigues, LSU Health Sciences Ctr, New Orleans, LA
10:10 am
Deletion of the Alpha Subunit of EnNaC and MTORC2 Inhibition Attenuate DOCA-Salt-Induced Endothelial Cell and Vascular Stiffness
Liping Zhang, Yan Yang, Annayya Aroor, Guanghong Jia, Zhe Sun, Univ of Missouri, Columbia, MO; Benjamin Bonnard, CRC, Paris, France; Francisco Ramirez, Univ of Missouri, Columbia, MO; Luis Arturo Martinez-Lemus, Univ of Missouri-Columbia, Columbia, MO; Frederic Jaisser, INSERM DR6, Paris, France; James Sowers, Michael A. Hill, Univ of Missouri, Columbia, MO
10:20 am
Histone Deacetylases 1 and 2 Regulate Six2 Function To Maintain Nephron Progenitor Cells During Nephrogenesis
Hongbing Liu, Mahitha M. Koduri, Andrea Dragon, Chao Hui Chen, Samir S. El-Dahr, Tulane Univ, New Orleans, LA
10:30 am
Mouse Recombinant Soluble PRR-Induced Increase of Blood Pressure Is Sex-Dependent in High Fat-Fed Mice
Audrey A. Poupeau, Univ of Kentucky, Lexington, KY; Eva Gatineau, Univ Catholique de Louvain, Woluwe-Saint-Lambert, Belgium; Gertrude Arthur, Wen Su, Ming C. Gong, Frederique B. Yiannikouris, Univ of Kentucky, Lexington, KY
10:40 am
Role of Pro-saas Peptides in Salt Resistance
Megha Kumar, Gina Capece, George Washington Univ, Washington, DC; Prasad R. Konkalmatt, The George Washington Univ, Washington, DC; Xiaoxu Zheng, Laureano Asico, Pedro Jose, Ines Armando, George Washington Univ, Washington, DC
10:50 am
The Etiology of Inverse Salt Sensitivity of Blood Pressure: Mirna-485-5p Binds to the Dopamine Type 2 Receptor (d2R) Snp Rs6276 and Decreases D2R Expression
John J Gildea, Univ of Virginia, Charlottesville, VA; Peng Xu, Univ of Virginia, Charlottesville, VA; Katherine Schiermeyer, Univ of Virginia, Charlottesville, VA; Wei Yue, Univ of Virginia, Charlottesville, VA; Robert M. Carey, Univ of Virginia Health System, Charlottesville, VA; Pedro A. Jose, George Washington Univ Sch Med Health Sci, Washington, DC; Robin A. Felder IV, Univ of Virginia, Charlottesville, VA